Fig. 3. Characteristics of mitochondrial bioenergetics of WT and VDAC1^-/- H9c2 cells. (A) Cell mitochondrial stress test profile plot. (B) Traces of O₂ consumption rate (OCR) in WT and VDAC1^-/-C1, C2 and C3 H9c2 cells under normal conditions measured using the Seahorse XFp Analyzer. (C) Individual parameters for basal respiration, maximal respiration, ATP production and spare respiratory capacity for WT and VDAC1^-/-C1, C2 and C3 H9c2 cells. Data are expressed as means ± SEM, n = 8 wells from 2 independent experiments.